Pearl AI does not publish a pricing page, which makes it one of the most-Googled "how much does it cost?" questions in dental software. After pulling together third-party listings, partner promotions, and case studies, here is the clearest picture available in 2026 of what Pearl actually costs a single-location practice, a multi-doctor group, and an enterprise DSO — and whether the math holds up against the production lift Pearl claims.
If you want the full feature deep-dive first, start with our Pearl review. This page focuses purely on the money.
Pricing Overview
Pearl sells two flagship products and a handful of add-ons. Each is priced separately, and the company prefers to quote practices through a sales conversation rather than a checkout page. Based on third-party listings (GetApp, Capterra, Nerdisa, dental software guides) and Patterson Dental promotional materials, here is what the public data shows:
- Second Opinion (real-time radiographic AI) starts around $299 per month per location on a flat-rate subscription, according to GetApp's published listing. A free trial is available.
- Practice Intelligence (operational analytics layered on top of Second Opinion) is the more substantial line item, with third-party reviews citing roughly $549 per month (or about $494/month if prepaid) per office, plus a one-time historical AI analysis fee.
- Setup fees appear to land around $1,500 for Second Opinion, based on Patterson Dental's "50% off, save up to $750" promotion. The setup typically includes back-cataloging historical radiographs so the AI has a baseline for the practice.
- Smart Margin (insurance claim cleanup) and AI-powered insurance verification are quoted custom — there is no published list price.
- Enterprise and DSO pricing is volume-based and negotiated. PDS Health rolled Pearl out to 1,100+ locations and Coast Dental to 88 — those deals are clearly nothing like the single-practice rate card.
For a typical single-location general practice running Second Opinion plus Practice Intelligence, a reasonable budgeting estimate is $700–$900 per month in subscription costs after setup. Solo practices that only want the diagnostic layer can start closer to $300/month.
A note on accuracy: Pearl has not officially confirmed any of these numbers, and pricing in dental AI moves quickly. Always request a current quote before budgeting.
What's Included in Each Plan
Second Opinion
This is Pearl's core radiographic AI and the product most practices start with. The subscription includes:
- Real-time analysis of bitewings, periapicals, and panoramics (under 30 seconds per image)
- Detection across caries, calculus, periapical pathology, margin discrepancies, and bone-loss areas
- Color-coded overlays inside a secure browser viewer
- Tooth Parts mapping and patient-friendly comparison views for case presentation
- Exportable patient health reports
- Integration with most major imaging platforms (Dexis, Carestream, Apteryx, Eaglesoft Imaging, and others)
- 24/7 support via phone, email, and chat
- Historical analysis of existing radiographs at onboarding (covered by the setup fee)
Practice Intelligence
This is the analytics and revenue-recovery layer, and it sits on top of Second Opinion. The subscription includes:
- Continuous scanning of radiographs, treatment plans, and patient records to surface untreated conditions
- Smart call lists sorted by treatment urgency and case value
- AI-prioritized morning huddle agendas
- Chart auditing across the full patient base (Pearl describes this as 18 months of historical X-ray review)
- PMS integration for unscheduled-treatment recall workflows
- Operational dashboards for clinician performance and case acceptance trends
Add-Ons
- Smart Margin — automated review of restorative margins for quality control and insurance documentation. Custom quote.
- AI-powered insurance verification — pre-visit benefits checks. Custom quote.
- 3D / CBCT analysis — Pearl holds the broadest FDA clearance in dental AI, including 3D. Pricing is bundled into enterprise deals.
Costs to Factor In Beyond the Sticker Price
Subscription fees are only part of the picture. A few line items practices should plan for:
- One-time setup fee. Roughly $1,500 for Second Opinion, including historical radiograph analysis. Watch Patterson Dental's promotional cycles — 50% setup discounts have appeared more than once.
- Historical AI analysis for Practice Intelligence. Third-party reviews cite a one-time $500 per office fee on top of the monthly subscription, separate from the Second Opinion setup.
- Imaging platform compatibility check. Pearl integrates with most major imaging systems, but practices on niche or older platforms may need a brief integration scoping call.
- Team training time. Pearl handles installation and onboarding, but the practice still invests staff hours in workflow adjustments — particularly for front-office teams adopting Practice Intelligence call lists.
- Annual vs. monthly billing. Practice Intelligence carries roughly a 10% discount when prepaid annually based on third-party listings ($494 vs. $549). Worth the math if cash flow allows.
- Multi-location pricing. If you operate more than one office, ask for a multi-site quote up front — per-location rates typically drop with scale.
- No long-term lock-in. Multiple third-party reviews note that Pearl does not require multi-year contracts, which lowers the commitment risk if a practice wants to pilot the platform.
These aren't surprises so much as line items that get missed when comparing Pearl against tools that quote a single all-in number.



